Department of Biology, The Chinese University of Hong Kong

Extracurricular Activities

Summer Course For Six Formers

Young Scholar Programme

CUHK > Department of Biology > People: Teaching Staffs |

Honorary Professor in Chinese Medicine (School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong)

Visiting Professor in Microbiology (Microbiology, Naikai University, PRC)

Associate Professor (Dept of Biology, The Chinese University of Hong Kong, Hong Kong)

Senior Lecturer (Dept of Biology, The Chinese University of Hong Kong, Hong Kong)

Visiting Assistant Professor (Microbiology & Molecular Genetics, Harvard Medical School, USA)

Lecturer (Dept of Biology, The Chinese University of Hong Kong, Hong Kong)

Postdoctoral Research Bacteriologist (Department of Bacteriology, University of California, Davis, USA)

Postdoctoral Research Microbiologist (Department of Food Science and Technology, University of California, Davis, USA)

Associate in Food Science & Technology (Department of Food Science and Technology, University of California, Davis, USA)

Student Demonstrator (Dept of Biology, The Chinese University of Hong Kong, Hong Kong)

Director (Molecular Biotechnology Programme, The Chinese University of Hong Kong, Hong Kong)

Associate Director (Molecular Biotechnology Programme, The Chinese University of Hong Kong, Hong Kong)

Head (Biology Graduate Division, Dept of Biology, The Chinese University of Hong Kong, Hong Kong)

Associate Director (Food and Nutritional Sciences Programme, The Chinese University of Hong Kong, Hong Kong)

Director (Food and Nutritional Sciences Programme, The Chinese University of Hong Kong, Hong Kong)

Dean of Students (United College, The Chinese University of Hong Kong, Hong Kong)

Director (Research Laboratory of Food Science, The Chinese University of Hong Kong, Hong Kong)

Director (Research Laboratory for Food Protein Production, The Chinese University of Hong Kong, Hong Kong)

Gonomics and functional genomics

Molecular biotechnology

Justices of the Peace (Hong Kong SAR Government)

Chairman (Expert Committee on Food Safety, FEDH, Hong Kong SAR Government)

Chairman (Accreditation Advisory Board, HKAS, Hong Kong SAR Government)

Deputy Director (Centre for Food and Drug Safety, Hong Kong SAR Government)

Member (Biology and Medicine Panel, Research Grants Council, University Grants Committee, Hong Kong SAR Government)

Member (Advisory Council on Food and Environmental Hygiene, Health, Welfare and Food Bureau, Hong Kong SAR Government)

Member (Publicity and Public Education Group on Clean Hong Kong, Environment and Food Bureau, Hong Kong SAR Government)

Member (Steering Committee on Clean Hong Kong, Environment and Food Bureau, Hong Kong SAR Government)

Member (Election Committee for 10th & 11th National People’s Congress of People’s Republic of China, Hong Kong SAR, PRC)

Member (Election Committee for Legislative Council and Chief Executive, Hong Kong SAR Government)

Tong, J., Chu, K.H. and Kwan, H.S. (2003) A mini-review of studies on genetic basis of sex determination in fish. Journal of Fisheries of China 27:169-176.

Kwan, H.S. and Xu, H.L. (2002) Construction of a genetic linkage map of Shiitake mushroom Lentinula edodes strain L-54. Journal of Biochemistry and Molecular Biology 35:465-471.

Tong, J., Lehnert, S.A., Byrne, K., Kwan, H.S. and Chu, K.H. (2002) Development of polymorphic EST markers in Penaeus monodon: applications in penaeid genetics. Aquaculture 208:69-79.

Woo, A.Y.H., Jiang, J.M., Chau, C.F., Waye, M.M.Y., Cheung, W.T., Kwan, H.S., and Cheng, C.H.K. (2001) Inotropic and chronotropic actions of Ilex latifolia inhibition of adenosine-5'-triphosphaatases as a possible mechanism. Life Sciences 68:1259-1270.

Zhao, J., Chen, Y.H. and Kwan, H.S. (2000) Molecular cloning, Characterization, and differential expression of a glucoamylase gene from the edible mushroom Lentinula edodes. Applied and Environmental Microbiology 66: 2531-2535.

Ng, W.L., Ng K.T.P. and Kwan, H.S. (2000) Developmental regulation of two hydrophobins in Lentinula edode. FEMS Microbiology Letters 185:139-145.

Leung, G.S.W., Zhang, M., Xie, W.J. and Kwan, H.S. (2000) Differentially expressed genes during the development of the basidiomycete Lentinula edodes identified by RNA fingerprinting. Molecular and General Genetics 262:977-990.

Zhao, J. and Kwan, H.S. (1999) Characterization, molecular cloning and differential expression analysis of laccase genes from the edible mushroom Lentinula edodes. Applied and Environmental Microbiology 65:4908-4913.

Leung, G.S.W., Zhang, M., Xie, W.J. and Kwan, H.S. (1999) Genes differentially expressed during fruit body development of Shiitake mushroom Lentinula edodes. In: Food for Health in the Pacific Rim (Whitaker, J.R. ed.), pp.553-559. Food and Nutrition Press, Inc.

Leung, P.S.C., Chen, Y.C., Gershwin, M.E., Wong, S.H., Kwan, H.S. and Chu, K.H. (1998) Identification and molecular characterization of Charybdis feriatus tropomyosin: The major crab allergen. Journal of Allergy and Clinical Immunology 102:847-852.

Zhang, M., Xie,W.J., Leung, G.S.W., Deane, E. and Kwan, H.S. (1998) Cloning and characterization of the gene encoding beta subunit of mitochondrial processing peptidase from the basidiomycete Lentinula edodes. Gene 206:23-27.

Leung, P.S.C., Chow, W.K., Duffey, S., Kwan, H.S., Gershwin, M.E. and Chu, K.H. (1996) IgE reactivity against a cross-reactive allergen in crustacea and mollusca: evidence for tropomyosin as the common allergen. Journal of Allergy and Clinical Immunology 98:954-961.

Chu, K.H., Chow, W.K., Kwan, H.S., Nagy, S.M., Gershwin, M.E. and Leung, P.S.C. (1995) Molecular cloning of the major heat-stable allergen from Metapenaeus ensis. Journal of Marine Biotechnology 3:126-129.

Chang, S.T., Kwan, H.S., Kang, Y.N., (1995) Collection, characterization and utilization of germplasm of Lentinus. Canadian Journal of Botany 73:S955-S961.

Leung, P.S.C., Chu, K.H., Chow, W.K., Ansari, A., Bindea, C., Kwan, H.S., Nagy, S.M. and Gershwin, M.E. (1994) Cloning, expression and primary structure of Metapenaeus ensis tropomyosin, the major heat stable shrimp allergen. Journal of Allergy and Clinical Immunology 94:882-890.

Kwan, H.S., So, K.H., Chan K.Y. and Cheng, S.C. (1993) Production of thermotolerant

-amylase by Bacillus circulans. World Journal of Microbiology and Biotechnology 9:50-52.

Dong, J., Iuchi, S., Kwan, H.S. and Lin, E.C.C. (1993) The deduced amino-acid sequence of the cloned cpxR gene suggests the protein is the cognate regulator for the membrane sensor, CpxA, in a two-component signal transduction system of Escherichia coli. Gene 136:227-230.

Kwan, H.S., Chiu S.W., Pang, K.M. and Cheng, S.C. (1992) Strain typing in Lentinula edodes by polymerase chain reaction. Experimental Mycology 16:163-166.

Wong, K.K. and Kwan, H.S. (1992) Anaerobic induction of glpT of Escherichia coli K12 from the cloned promoter in promoter-probe plasmid pFZY1. FEMS Microbiology Letters 94:15-18.

Wong, K.K., Suen, K.L. and Kwan, H.S. (1989) Transcription of pfl is regulated byanaerobiosis, catabolite repression, pyruvate and oxrA: pfl ::Mu d A operon fusions of Salmonella typhimurium. Journal of Bacteriology 171:4900-4905.

Kwan, H.S., Chui, H.W. and Wong, K.K. (1988) ack ::Mu d 1-8(Ap^r lac) operon fusions of Salmonella typhimurium LT2. Molecular and General Genetics 211:183-185.

Riggs, D.L., Mueller, R.D., Kwan, H.S. and Artz, S.W. (1986) Promoter domain mediates guanosine tetraphosphate activation of the histidine operon. Proceedings of National Academy of Science, USA 83:9333-9337.

Kwan, H.S. and Wong, K.K. (1986) A general method for isolation of Mu d 1-8(Ap^rlac) fusions in Salmonella typhimurium LT2 from Tn10 insertions: chlC::Mu d 1-8 fusions. Molecular and General Genetics 205:221-224.

Barrett, E.L. and Kwan, H.S. (1985) Bacterial reduction of trimethylamine oxide. Annual Review of Microbiology 39:131-149.

Plant and Fungal Biotechnology - HK$38,823,000 (co-investigator)

Automated Microbial Identification Systems - HK$2,980,000 (co-investigator)

Automated Genetic Analysis System - HK$3,000,000 (co-investigator)

Role of the brownish shiitake mycelia exudate on the cell death of Leukemia cell line and its role as an antioxidant and a functional food colorant HK$920,500 (Co-investigator – PI: Prof H Y Chung)

Mushroom Non-digestible Carbohydrates as Novel β-Glucan Type Prebiotics: Their Preparation and In Vitro Microbial Fermentation HK$718,957 (Co-investigator – PI: Prof Peter Cheung)

Gene expression during ovarian maturation in penaeid shrimp - HK$1,697,600 (co-investigator - collaborator: Prof KH Chu)

Identification and characterization of genes differentially expressed in dikaryotic mycelium of Shiitake Mushroom Lentinula edodes by cDNA microarray hybridization - HK$771,100

Elucidation of Gene Expression Profiles during Fruit Body Development of Shiitake Mushroom Lentinula edodes using Expressed Sequence Tags and Serial Analysis of Gene Expression - HK$600,000

Development of Molecular Makers for Genome Mapping in Penaeid Shrimp - HK$600,000 (co-investigator - collaborator: Prof KH Chu)

Yeast Complementation Analyses of Signal Transduction Genes Isolated from Early Fruit Body Development of Shiitake Mushroom Lentinula edodes - HK$780,840

Molecular Studies on Shellfish Allergies: Cloning, Sequencing and Immunological Responses - HK$686,880 (co-investigator - collaborator: Prof KH Chu)

Development of a Species Genetic Linkage Map of the Shiitake Mushroom Lentinula edodes with Sequence-tagged-site, Expressed-sequence-tag, and Gene Markers - HK$692,000

Molecular Cloning and Time Course Studies of Genes Specially Expressed during Fruit Body Development in Shiitake Mushroom Lentinula edodes - HK$713,000

Identification and Molecular Cloning of Differentially Expressed Genes Involved in Lignocellulose Utilization in Shiitake Mushroom Lentinula dodes - HK$583,000 (collaborator: Prof J Peberdy)

Generation of Molecular Markers for Construction of a Genetic Map and Characterization of Genetic Determinants of some Phenotypic Traits in Shiitake Mushroom Lentinula edodes - HK$756,000

Ethanol Production by Anaerobic Fermentation in Genetically Manipulated Terrestrial and Marine Enteric Bacteria - HK$250,000 (collaborator: Dr KY Chan)

Removal of Heavy Metals from Wastewater by Immobilized Microbial Cells - HK$500,000 (co-investigator - collaborators: Drs PK Wong, KY Chan and KC Lam)

Development of Over-the-counter Pharmaceutical Products based on Local medicinal plants - HK$9,128,000 (co-principal investigator - collaborator: Prof YC Kong)

Molecular Cloning and Expression of Crustacean Allergens - HK$600,000 (co-investigator - collaborator: Dr KH Chu)

Regulation of Cellulase Genes in the Oyster Mushroom Pleurotus - HK$100,000 (co-investigator -collaborators: Profs JF Peberdy, ST Cheung and JA Buswell)

Establishment of the Genomic Library, Linkage Map and Germplasm Bank for Lentinula edodes HK$627,000

Gene Cloning and Production of Thermo-stable β-amylase in Bacillus subtilis - HK$420,000 (collaborator: Dr KY Chan)

Genes Controlling the Switch to Anaerobic Metabolism - HK$243,000 (1986-89), HK$60,000 (1989-1992) (co-investigator - collaborator: Drs KK Mark and WKK Ho)

Research and laboratory work on the Chinese medicinal herb, Radix Astragali - HK$338,000

Research and laboratory work on the Chinese medicinal herb, Cortex Moutan - HK$338,000

Research and laboratory work on the Chinese medicinal herb, Cortex Phellodendri - HK$338,000

Research and laboratory work on the Chinese medicinal herb, Rhizoma Alismatis - HK$338,000

Research and laboratory work on the Chinese medicinal herb, Rhizoma Cimicifugae - HK$381,350

Research and laboratory work on the Chinese medicinal herb, Radix Paeonia rubra - HK$381,350

Research and laboratory work on the Chinese medicinal herb, Radix Paeonia alba - HK$381,350

Research and laboratory work on the Chinese medicinal herb, Radix Aucklandiae - HK$381,350

Construction of Food Composition Database - HK$17,770,000 (principal investigator)

A Science Enrichment Programme for secondary 3-4 Students - HK$2,000,000 (principal investigator)

Promoting the Use of the Outcome-based Approach in Science Programmes: Development of Learning Outcome Statements and Measurment Instruments - HK$800,000 (principal investigator)

Engaging Science Studies in the Design and Enactment of Assessment - HK$160,000 (principal investigator)

Case-based Learning of High School Science Subjects to Support Learning to Learn - HK$2,820,000 (principal investigator)

Molecular Method Development for Authentication of the "Thai Hom Mali Rice" (Khao Dawk Mali 105 and RD15), Based on Rice Samples (ParkNShop, Supermarkets of Hutchison Whampoa Limited) HK$60,000

Genetic Diversity Analysis of Cuora trifasciata and its Allied Species Using Microsatellite Markers Developed from Mauremys rivulata (Agriculture, Fisheries & Conservation Department, HKSAR Government) HK$50,000

Analysis of Fermented Shrimp Sauce and Fermented Soybean Sauce (Lee Kum Kee Co Ltd) HK$90,000

Authenification of biologic materials using DNA-DNA hybridization on a solid support (principal investigator) (US patent #7297490, 2008)

Last updated:June 3, 2008